A crowd-sourcing approach for the construction of species-specific cell signaling networks

Motivation: Animal models are important tools in drug discovery and for understanding human biology in general. However, many drugs that initially show promising results in rodents fail in later stages of clinical trials. Understanding the commonalities and differences between human and rat cell sig...

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Veröffentlicht in:Bioinformatics
Hauptverfasser: Bilal, Erhan, Sakellaropoulos, Theodore, Participants, Challenge, Melas, Ioannis N., Messinis, Dimitris E., Belcastro, Vincenzo, Rhrissorrakrai, Kahn, Meyer, Pablo, Norel, Raquel, Iskandar, Anita, Blaese, Elise, Rice, John J., Peitsch, Manuel C., Hoeng, Julia, Stolovitzky, Gustavo, Alexopoulos, Leonidas G., Poussin, Carine
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Improver Challenge Special Issue; Species Translation Challenge
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325542/
https://ncbi.nlm.nih.gov/pubmed/25294919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu659
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