A crowd-sourcing approach for the construction of species-specific cell signaling networks

Motivation: Animal models are important tools in drug discovery and for understanding human biology in general. However, many drugs that initially show promising results in rodents fail in later stages of clinical trials. Understanding the commonalities and differences between human and rat cell sig...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Bioinformatics
المؤلفون الرئيسيون: Bilal, Erhan, Sakellaropoulos, Theodore, Participants, Challenge, Melas, Ioannis N., Messinis, Dimitris E., Belcastro, Vincenzo, Rhrissorrakrai, Kahn, Meyer, Pablo, Norel, Raquel, Iskandar, Anita, Blaese, Elise, Rice, John J., Peitsch, Manuel C., Hoeng, Julia, Stolovitzky, Gustavo, Alexopoulos, Leonidas G., Poussin, Carine
التنسيق: Artigo
اللغة:Inglês
منشور في: Oxford University Press 2015
الموضوعات:
Improver Challenge Special Issue; Species Translation Challenge
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325542/
https://ncbi.nlm.nih.gov/pubmed/25294919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu659
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