Understanding the limits of animal models as predictors of human biology: lessons learned from the sbv IMPROVER Species Translation Challenge

Motivation: Inferring how humans respond to external cues such as drugs, chemicals, viruses or hormones is an essential question in biomedicine. Very often, however, this question cannot be addressed because it is not possible to perform experiments in humans. A reasonable alternative consists of ge...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Rhrissorrakrai, Kahn, Belcastro, Vincenzo, Bilal, Erhan, Norel, Raquel, Poussin, Carine, Mathis, Carole, Dulize, Rémi H. J., Ivanov, Nikolai V., Alexopoulos, Leonidas, Jeremy Rice, J., Peitsch, Manuel C., Stolovitzky, Gustavo, Meyer, Pablo, Hoeng, Julia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Improver Challenge Special Issue; Species Translation Challenge
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325540/
https://ncbi.nlm.nih.gov/pubmed/25236459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu611
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