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Understanding the limits of animal models as predictors of human biology: lessons learned from the sbv IMPROVER Species Translation Challenge

Motivation: Inferring how humans respond to external cues such as drugs, chemicals, viruses or hormones is an essential question in biomedicine. Very often, however, this question cannot be addressed because it is not possible to perform experiments in humans. A reasonable alternative consists of ge...

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Dettagli Bibliografici
Pubblicato in:Bioinformatics
Autori principali: Rhrissorrakrai, Kahn, Belcastro, Vincenzo, Bilal, Erhan, Norel, Raquel, Poussin, Carine, Mathis, Carole, Dulize, Rémi H. J., Ivanov, Nikolai V., Alexopoulos, Leonidas, Jeremy Rice, J., Peitsch, Manuel C., Stolovitzky, Gustavo, Meyer, Pablo, Hoeng, Julia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325540/
https://ncbi.nlm.nih.gov/pubmed/25236459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu611
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