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Inter-species pathway perturbation prediction via data-driven detection of functional homology
Motivation: Experiments in animal models are often conducted to infer how humans will respond to stimuli by assuming that the same biological pathways will be affected in both organisms. The limitations of this assumption were tested in the IMPROVER Species Translation Challenge, where 52 stimuli we...
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| Veröffentlicht in: | Bioinformatics |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4325539/ https://ncbi.nlm.nih.gov/pubmed/25150249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu570 |
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