Understanding the limits of animal models as predictors of human biology: lessons learned from the sbv IMPROVER Species Translation Challenge

Motivation: Inferring how humans respond to external cues such as drugs, chemicals, viruses or hormones is an essential question in biomedicine. Very often, however, this question cannot be addressed because it is not possible to perform experiments in humans. A reasonable alternative consists of ge...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Bioinformatics
Main Authors: Rhrissorrakrai, Kahn, Belcastro, Vincenzo, Bilal, Erhan, Norel, Raquel, Poussin, Carine, Mathis, Carole, Dulize, Rémi H. J., Ivanov, Nikolai V., Alexopoulos, Leonidas, Jeremy Rice, J., Peitsch, Manuel C., Stolovitzky, Gustavo, Meyer, Pablo, Hoeng, Julia
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2015
נושאים:
Improver Challenge Special Issue; Species Translation Challenge
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325540/
https://ncbi.nlm.nih.gov/pubmed/25236459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu611
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