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Using Solutes and Kinetics to Probe Large Conformational Changes in the Steps of Transcription Initiation
Small solutes are useful probes of large conformational changes in RNA polymerase (RNAP)-promoter interactions and other biopolymer processes. In general, a large effect of a solute on an equilibrium constant (or rate constant) indicates a large change in water-accessible biopolymer surface area in...
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| Publicat a: | Methods Mol Biol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4324510/ https://ncbi.nlm.nih.gov/pubmed/25665568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2392-2_14 |
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