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RNA Polymerase: Step by Step Kinetics and Mechanism of Transcription Initiation

To determine the step-by-step kinetics and mechanism of transcription initiation and escape by E. coli RNA polymerase from the λPR promoter, we quantify the accumulation and decay of transient short RNA intermediates on the pathway to promoter escape and full-length (FL) RNA synthesis over a wide ra...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Henderson, Kate L., Evensen, Claire E., Molzahn, Cristen M., Felth, Lindsey C., Dyke, Sarah, Liao, Guanyu, Shkel, Irina A., Record, M. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504642/
https://ncbi.nlm.nih.gov/pubmed/30950601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00049
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