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Mechanism of transcription initiation and promoter escape by E. coli RNA polymerase
To investigate roles of the discriminator and open complex (OC) lifetime in transcription initiation by Escherichia coli RNA polymerase (RNAP; α(2)ββ’ωσ(70)), we compare productive and abortive initiation rates, short RNA distributions, and OC lifetime for the λP(R) and T7A1 promoters and variants w...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5393250/ https://ncbi.nlm.nih.gov/pubmed/28348246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618675114 |
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