Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1

Synaptic vesicle protein 2A (SV2A) is a ubiquitous component of synaptic vesicles (SVs). It has roles in both SV trafficking and neurotransmitter release. We demonstrate that Casein kinase 1 family members, including isoforms of Tau–tubulin protein kinases (TTBK1 and TTBK2), phosphorylate human SV2A...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Zhang, Ning, Gordon, Sarah L., Fritsch, Maximilian J., Esoof, Noor, Campbell, David G., Gourlay, Robert, Velupillai, Srikannathasan, Macartney, Thomas, Peggie, Mark, van Aalten, Daan M.F., Cousin, Michael A., Alessi, Dario R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323530/
https://ncbi.nlm.nih.gov/pubmed/25673844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4248-14.2015
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