PAWS1 controls Wnt signalling through association with casein kinase 1α

The BMP and Wnt signalling pathways determine axis specification during embryonic development. Our previous work has shown that PAWS1 (also known as FAM83G) interacts with SMAD1 and modulates BMP signalling. Here, surprisingly, we show that overexpression of PAWS1 in Xenopus embryos activates Wnt si...

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Veröffentlicht in:EMBO Rep
Hauptverfasser: Bozatzi, Polyxeni, Dingwell, Kevin S, Wu, Kevin ZL, Cooper, Fay, Cummins, Timothy D, Hutchinson, Luke D, Vogt, Janis, Wood, Nicola T, Macartney, Thomas J, Varghese, Joby, Gourlay, Robert, Campbell, David G, Smith, James C, Sapkota, Gopal P
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891436/
https://ncbi.nlm.nih.gov/pubmed/29514862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744807
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