PAWS1 controls Wnt signalling through association with casein kinase 1α

The BMP and Wnt signalling pathways determine axis specification during embryonic development. Our previous work has shown that PAWS1 (also known as FAM83G) interacts with SMAD1 and modulates BMP signalling. Here, surprisingly, we show that overexpression of PAWS1 in Xenopus embryos activates Wnt si...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Bozatzi, Polyxeni, Dingwell, Kevin S, Wu, Kevin ZL, Cooper, Fay, Cummins, Timothy D, Hutchinson, Luke D, Vogt, Janis, Wood, Nicola T, Macartney, Thomas J, Varghese, Joby, Gourlay, Robert, Campbell, David G, Smith, James C, Sapkota, Gopal P
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5891436/
https://ncbi.nlm.nih.gov/pubmed/29514862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744807
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