Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signalling

Bone morphogenetic proteins (BMPs) control multiple cellular processes in embryos and adult tissues. BMPs signal through the activation of type I BMP receptor kinases, which then phosphorylate SMADs 1/5/8. In the canonical pathway, this triggers the association of these SMADs with SMAD4 and their tr...

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Autori principali: Janis Vogt, Kevin S. Dingwell, Lina Herhaus, Robert Gourlay, Thomas Macartney, David Campbell, James C. Smith, Gopal P. Sapkota
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2014-01-01
Serie:Open Biology
Soggetti:
bone morphogenetic protein
smad1
fam83g
paws1
alk3
bmpr1
Accesso online:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.130210
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