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Sequence and structural determinants of human APOBEC3H deaminase and anti-HIV-1 activities
BACKGROUND: Human APOBEC3H (A3H) belongs to the A3 family of host restriction factors, which are cytidine deaminases that catalyze conversion of deoxycytidine to deoxyuridine in single-stranded DNA. A3 proteins contain either one (A3A, A3C, A3H) or two (A3B, A3D, A3F, A3G) Zn-binding domains. A3H ha...
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| Publicat a: | Retrovirology |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4323217/ https://ncbi.nlm.nih.gov/pubmed/25614027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-014-0130-8 |
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