Aurora B-dependent phosphorylation of Ataxin-10 promotes the interaction between Ataxin-10 and Plk1 in cytokinesis

Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant neurologic disorder caused by ATTCT expansion in the ATXN10 gene. Previous investigations have identified that depletion of Ataxin-10, the gene product, leads to cellular apoptosis and cytokinesis failure. Herein we identify the mitotic...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Tian, Jie, Tian, Chuan, Ding, Yuehe, Li, Zhe, Geng, Qizhi, Xiahou, Zhikai, Wang, Jue, Hou, Wenya, Liao, Ji, Dong, Meng-Qiu, Xu, Xingzhi, Li, Jing
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322367/
https://ncbi.nlm.nih.gov/pubmed/25666058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08360
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares