Chk1 modulates the interaction between myosin phosphatase targeting protein 1 (MYPT1) and protein phosphatase 1cβ (PP1cβ)

Polo-like kinase 1 (Plk1) is an instrumental kinase that modulates many aspects of the cell cycle. Previous investigations have indicated that Plk1 is a target of the DNA damage response, and Plk1 inhibition is dependent on ATM/ATR and Chk1. But the exact mechanism remains elusive. In a proteomic sc...

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Dettagli Bibliografici
Pubblicato in:Cell Cycle
Autori principali: Hu, Xiaomei, Li, Zhe, Ding, Yuehe, Geng, Qizhi, Xiahou, Zhikai, Ru, Huanwei, Dong, Meng-Qiu, Xu, Xingzhi, Li, Jing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
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Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927650/
https://ncbi.nlm.nih.gov/pubmed/29262732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1418235
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