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Synthesis of 13,14-dehydroprostacyclin methyl ester: a potent inhibitor of platelet aggregation.

The structure of the most recently discovered, biologically highly active prostaglandin, PGI2 or prostacyclin, is correctly predicted on biogenetic grounds, and a general synthesis starting with prostaglandins of the F2alpha series is reported. Starting with the biologically active 13,14-dehydro-PGF...

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Bibliografiska uppgifter
Huvudupphovsmän: Fried, J, Barton, J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1977
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC432136/
https://ncbi.nlm.nih.gov/pubmed/267919
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