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THE TUMOR-PROMOTER PHORBOL ESTER (12-0-TETRADECANOYL-PHORBOL-13-ACETATE), A POTENT AGGREGATING AGENT FOR BLOOD PLATELETS

The phorbol ester 12-0-tetradecanoyl-phorbol-13-acetate, a potent tumor-promoting agent, caused irreversible platelet aggregation when more than 0.02 µM was stirred with human citrated or heparinized platelet-rich plasma (PRP). With washed platelets, 1 nM was effective. The alcohol phorbol, which ha...

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Detalhes bibliográficos
Main Authors: Zucker, Marjorie B., Troll, Walter, Belman, Sidney
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2109156/
https://ncbi.nlm.nih.gov/pubmed/4360292
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