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Synthesis of 13,14-dehydroprostacyclin methyl ester: a potent inhibitor of platelet aggregation.

The structure of the most recently discovered, biologically highly active prostaglandin, PGI2 or prostacyclin, is correctly predicted on biogenetic grounds, and a general synthesis starting with prostaglandins of the F2alpha series is reported. Starting with the biologically active 13,14-dehydro-PGF...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Fried, J, Barton, J
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1977
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/267919/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.6.2199
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