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Targeting the pregnane X receptor in liver injury (review)
INTRODUCTION: The nuclear receptor pregnane X receptor (PXR) is a well-characterized hepatic xenobiotic sensor whose activation by chemically diverse compounds results in the induction of drug clearance pathways that rid the body of potentially toxic substances, thus conferring protection from forei...
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| Publicat a: | Expert Opin Ther Targets |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319648/ https://ncbi.nlm.nih.gov/pubmed/22913318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2012.715634 |
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