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Targeting the pregnane X receptor in liver injury (review)
INTRODUCTION: The nuclear receptor pregnane X receptor (PXR) is a well-characterized hepatic xenobiotic sensor whose activation by chemically diverse compounds results in the induction of drug clearance pathways that rid the body of potentially toxic substances, thus conferring protection from forei...
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| Publicado no: | Expert Opin Ther Targets |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319648/ https://ncbi.nlm.nih.gov/pubmed/22913318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2012.715634 |
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