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Pregnane X receptor and drug-induced liver injury
INTRODUCTION: The liver plays a central role in transforming and clearing foreign substances. The continuous exposure of the liver to xenobiotics sometimes leads to impaired liver function, referred to as drug-induced liver injury (DILI). The pregnane X receptor (PXR) tightly regulates the expressio...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4198438/ https://ncbi.nlm.nih.gov/pubmed/25252616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2014.963555 |
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