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Strategies for developing pregnane X receptor antagonists: Implications from metabolism to cancer
Pregnane X receptor (PXR) is a ligand-activated nuclear receptor that was originally identified as a master regulator of xenobiotic detoxification. It regulates the expression of drug-metabolizing enzymes and transporters to control the degradation and excretion of endobiotics and xenobiotics, inclu...
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| Pubblicato in: | Med Res Rev |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7166136/ https://ncbi.nlm.nih.gov/pubmed/31782213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.21648 |
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