ロード中...
Small Molecules Dorsomorphin and LDN-193189 Inhibit Myostatin/GDF8 Signaling and Promote Functional Myoblast Differentiation
GDF8, or myostatin, is a member of the TGF-β superfamily of secreted polypeptide growth factors. GDF8 is a potent negative regulator of myogenesis both in vivo and in vitro. We found that GDF8 signaling was inhibited by the small molecule ATP competitive inhibitors dorsomorphin and LDN-193189. These...
保存先:
| 出版年: | J Biol Chem |
|---|---|
| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2015
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319009/ https://ncbi.nlm.nih.gov/pubmed/25368322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.604397 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|