Structure of the Bone Morphogenetic Protein Receptor ALK2 and Implications for Fibrodysplasia Ossificans Progressiva

Bone morphogenetic protein (BMP) receptor kinases are tightly regulated to control development and tissue homeostasis. Mutant receptor kinase domains escape regulation leading to severely degenerative diseases and represent an important therapeutic target. Fibrodysplasia ossificans progressiva (FOP)...

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Bibliografski detalji
Glavni autori: Chaikuad, Apirat, Alfano, Ivan, Kerr, Georgina, Sanvitale, Caroline E., Boergermann, Jan H., Triffitt, James T., von Delft, Frank, Knapp, Stefan, Knaus, Petra, Bullock, Alex N.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Protein Structure and Folding
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481300/
https://ncbi.nlm.nih.gov/pubmed/22977237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365932
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