Structure of the Bone Morphogenetic Protein Receptor ALK2 and Implications for Fibrodysplasia Ossificans Progressiva

Bone morphogenetic protein (BMP) receptor kinases are tightly regulated to control development and tissue homeostasis. Mutant receptor kinase domains escape regulation leading to severely degenerative diseases and represent an important therapeutic target. Fibrodysplasia ossificans progressiva (FOP)...

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Detaylı Bibliyografya
Asıl Yazarlar: Chaikuad, Apirat, Alfano, Ivan, Kerr, Georgina, Sanvitale, Caroline E., Boergermann, Jan H., Triffitt, James T., von Delft, Frank, Knapp, Stefan, Knaus, Petra, Bullock, Alex N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2012
Konular:
Protein Structure and Folding
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481300/
https://ncbi.nlm.nih.gov/pubmed/22977237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365932
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