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Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad, p38 and Akt signalling in C2C12 cells
Bone morphogenetic proteins (BMPs) are key regulators of cell fate decisions during embryogenesis and tissue homeostasis. BMPs signal through a coordinated assembly of two types of transmembrane serine/ threonine kinase receptors to induce Smad1/5/8 plus non-Smad pathways, such as MAPK and Akt. The...
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| Pubblicato in: | Int J Biochem Cell Biol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6164168/ https://ncbi.nlm.nih.gov/pubmed/20691279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2010.07.018 |
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