The Bone Morphogenetic Protein Signaling Inhibitor LDN-193189 Enhances Metastasis Development in Mice

Breast cancer with bone metastasis is essentially incurable with current anticancer therapies. The bone morphogenetic protein (BMP) pathway is an attractive therapeutic candidate, as it is involved in the bone turnover and in cancer cell formation and their colonization of distant organs such as the...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Vollaire, Julien, Machuca-Gayet, Irma, Lavaud, Jonathan, Bellanger, Aurélie, Bouazza, Lamia, El Moghrabi, Soumaya, Treilleux, Isabelle, Coll, Jean-Luc, Peyruchaud, Olivier, Josserand, Véronique, Cohen, Pascale A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593094/
https://ncbi.nlm.nih.gov/pubmed/31275146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00667
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