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The Bone Morphogenetic Protein Signaling Inhibitor LDN-193189 Enhances Metastasis Development in Mice

Breast cancer with bone metastasis is essentially incurable with current anticancer therapies. The bone morphogenetic protein (BMP) pathway is an attractive therapeutic candidate, as it is involved in the bone turnover and in cancer cell formation and their colonization of distant organs such as the...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Vollaire, Julien, Machuca-Gayet, Irma, Lavaud, Jonathan, Bellanger, Aurélie, Bouazza, Lamia, El Moghrabi, Soumaya, Treilleux, Isabelle, Coll, Jean-Luc, Peyruchaud, Olivier, Josserand, Véronique, Cohen, Pascale A.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593094/
https://ncbi.nlm.nih.gov/pubmed/31275146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00667
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