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Not just gRASping at flaws: Finding vulnerabilities to develop novel therapies for treating KRAS mutant cancers
Mutations in Kirsten rat-sarcoma (KRAS) are well appreciated to be major drivers of human cancers through dysregulation of multiple growth and survival pathways. Similar to many other non-kinase oncogenes and tumor suppressors, efforts to directly target KRAS pharmaceutically have not yet materializ...
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| Publicado no: | Cancer Sci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4317830/ https://ncbi.nlm.nih.gov/pubmed/24612015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12383 |
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