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gRASping the redox lever to modulate cancer cell fate signaling

RAS proteins are critical regulators of signaling networks controlling diverse cellular functions such as cell proliferation and survival and its mutation are among the most powerful oncogenic drivers in human cancers. Despite intense efforts, direct RAS-targeting strategies remain elusive due to it...

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Détails bibliographiques
Publié dans:Redox Biol
Auteurs principaux: Foo, Chuan Han Jonathan, Pervaiz, Shazib
Format: Artigo
Langue:Inglês
Publié: Elsevier 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859584/
https://ncbi.nlm.nih.gov/pubmed/30638892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.101094
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