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gRASping the redox lever to modulate cancer cell fate signaling

RAS proteins are critical regulators of signaling networks controlling diverse cellular functions such as cell proliferation and survival and its mutation are among the most powerful oncogenic drivers in human cancers. Despite intense efforts, direct RAS-targeting strategies remain elusive due to it...

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Detalles Bibliográficos
Publicado en:Redox Biol
Main Authors: Foo, Chuan Han Jonathan, Pervaiz, Shazib
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859584/
https://ncbi.nlm.nih.gov/pubmed/30638892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.101094
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