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Metallothionein Blocks Oxidative DNA Damage Induced by Acute Inorganic Arsenic Exposure

We studied how the protein metallothionein (MT) impacts arsenic-induced oxidative DNA damage (ODD) using cells that poorly express MT (MT-I/II double knockout embryonic cells; called MT-null cells) and wild-type (WT) MT competent cells. Arsenic (as NaAsO(2)) was less cytolethal over 24 h in WT cells...

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Bibliografiska uppgifter
I publikationen:Toxicol Appl Pharmacol
Huvudupphovsmän: Qu, Wei, Waalkes, Michael P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315697/
https://ncbi.nlm.nih.gov/pubmed/25485709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.11.014
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