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Metallothionein blocks oxidative DNA damage in vitro

The role of metallothionein (MT) in mitigation of oxidative DNA damage (ODD) induced either by cadmium (Cd) or the direct oxidant hydrogen peroxide (H(2)O(2)) was systematically examined by using MT-I/II double knockout (MT-null) or MT-competent wild-type (WT) cells. Both toxicants were much more le...

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Detalhes bibliográficos
Main Authors: Qu, Wei, Pi, Jingbo, Waalkes, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554841/
https://ncbi.nlm.nih.gov/pubmed/22914987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-012-0927-y
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