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Metallothionein Blocks Oxidative DNA Damage Induced by Acute Inorganic Arsenic Exposure
We studied how the protein metallothionein (MT) impacts arsenic-induced oxidative DNA damage (ODD) using cells that poorly express MT (MT-I/II double knockout embryonic cells; called MT-null cells) and wild-type (WT) MT competent cells. Arsenic (as NaAsO(2)) was less cytolethal over 24 h in WT cells...
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| Publicado no: | Toxicol Appl Pharmacol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4315697/ https://ncbi.nlm.nih.gov/pubmed/25485709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.11.014 |
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