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Methylarsonous acid causes oxidative DNA damage in cells independent of the ability to biomethylate inorganic arsenic
Inorganic arsenic (iAs) and its toxic methylated metabolite, methylarsonous acid (MMA(III)), both have carcinogenic potential. Prior study shows iAs induced malignant transformation in both arsenic methylation-proficient (liver) and methylation-deficient (prostate) cells, but only methylation-profic...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3946729/ https://ncbi.nlm.nih.gov/pubmed/24091636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-013-1141-2 |
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