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STEP(61) is a substrate of the E3 ligase parkin and is upregulated in Parkinson’s disease
Parkinson’s disease (PD) is characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNc). The loss of SNc dopaminergic neurons affects the plasticity of striatal neurons and leads to significant motor and cognitive disabilities during the progression of the d...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4313846/ https://ncbi.nlm.nih.gov/pubmed/25583483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417423112 |
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