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Rapid RNA Strand Scission Following C2′-Hydrogen Atom Abstraction
C2′-Nucleotide radicals have been proposed as key intermediates in direct strand break formation in RNA exposed to ionizing radiation. Uridin-2′-yl radical (1) was independently generated in single- and double-stranded RNA via photolysis of a ketone precursor. Direct stand breaks result from heterol...
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| 出版年: | J Am Chem Soc |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4313564/ https://ncbi.nlm.nih.gov/pubmed/25580810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja511401g |
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