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Direct Strand Scission from a Nucleobase Radical in RNA

[Image: see text] RNA oxidation is important in the etiology of disease and as a tool for studying the structure and folding kinetics of this biopolymer. Nucleobase radicals are the major family of reactive intermediates produced in RNA exposed to diffusible species such as hydroxyl radical. The nuc...

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Detalhes bibliográficos
Main Authors: Jacobs, Aaron C., Resendiz, Marino J. E., Greenberg, Marc M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845440/
https://ncbi.nlm.nih.gov/pubmed/20184313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja100281x
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