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Rapid RNA Strand Scission Following C2′-Hydrogen Atom Abstraction

C2′-Nucleotide radicals have been proposed as key intermediates in direct strand break formation in RNA exposed to ionizing radiation. Uridin-2′-yl radical (1) was independently generated in single- and double-stranded RNA via photolysis of a ketone precursor. Direct stand breaks result from heterol...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Am Chem Soc
Päätekijät: Paul, Rakesh, Greenberg, Marc M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313564/
https://ncbi.nlm.nih.gov/pubmed/25580810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja511401g
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