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Direct Strand Scission in Double Stranded RNA via a C5-Pyrimidine Radical

Nucleobase radicals are the major family of reactive intermediates produced when nucleic acids are exposed to γ-radiolysis. 5,6-Dihydrouridin-5-yl radical (1), the formal product of hydrogen atom addition and a model for hydroxyl radical addition was independently generated from a ketone precursor v...

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Bibliografiske detaljer
Main Authors: Resendiz, Marino J. E., Pottiboyina, Venkata, Sevilla, Michael D., Greenberg, Marc M.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315363/
https://ncbi.nlm.nih.gov/pubmed/22335525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja300044e
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