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Direct Strand Scission in Double Stranded RNA via a C5-Pyrimidine Radical
Nucleobase radicals are the major family of reactive intermediates produced when nucleic acids are exposed to γ-radiolysis. 5,6-Dihydrouridin-5-yl radical (1), the formal product of hydrogen atom addition and a model for hydroxyl radical addition was independently generated from a ketone precursor v...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3315363/ https://ncbi.nlm.nih.gov/pubmed/22335525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja300044e |
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