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Heparanase mediates a novel mechanism in lapatinib-resistant brain metastatic breast cancer()()
Heparanase (HPSE) is the dominant mammalian endoglycosidase and important tumorigenic, angiogenic, and pro-metastatic molecule. Highest levels of HPSE activity have been consistently detected in cells possessing highest propensities to colonize the brain, emphasizing the therapeutic potential for ta...
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| Udgivet i: | Neoplasia |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Neoplasia Press
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4309682/ https://ncbi.nlm.nih.gov/pubmed/25622903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.11.007 |
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