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Effect of Lapatinib on the Outgrowth of Metastatic Breast Cancer Cells to the Brain

BACKGROUND: The brain is increasingly being recognized as a sanctuary site for metastatic tumor cells in women with HER2-overexpressing breast cancer who receive trastuzumab therapy. There are no approved or widely accepted treatments for brain metastases other than steroids, cranial radiotherapy, a...

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Main Authors: Gril, Brunilde, Palmieri, Diane, Bronder, Julie L., Herring, Jeanne M., Vega-Valle, Eleazar, Feigenbaum, Lionel, Liewehr, David J., Steinberg, Seth M., Merino, Maria J., Rubin, Stephen D., Steeg, Patricia S.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575427/
https://ncbi.nlm.nih.gov/pubmed/18664652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djn216
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