Pazopanib Inhibits the Activation of PDGFRβ-Expressing Astrocytes in the Brain Metastatic Microenvironment of Breast Cancer Cells

Brain metastases occur in more than one-third of metastatic breast cancer patients whose tumors overexpress HER2 or are triple negative. Brain colonization of cancer cells occurs in a unique environment, containing microglia, oligodendrocytes, astrocytes, and neurons. Although a neuroinflammatory re...

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Detalhes bibliográficos
Main Authors: Gril, Brunilde, Palmieri, Diane, Qian, Yongzhen, Anwar, Talha, Liewehr, David J., Steinberg, Seth M., Andreu, Zoraida, Masana, Daniel, Fernández, Paloma, Steeg, Patricia S., Vidal-Vanaclocha, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668025/
https://ncbi.nlm.nih.gov/pubmed/23583652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.02.043
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