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MicroRNA-1258 Suppresses Breast Cancer Brain Metastasis by Targeting Heparanase

Heparanase (HPSE) is a potent pro-tumorigenic, pro-angiogenic and pro-metastatic enzyme that is overexpressed in brain metastatic breast cancer (BMBC). However, little is known about the regulation of this potential therapeutic target in BMBC, which remains very poorly managed in the clinic. We hypo...

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Sonraí Bibleagrafaíochta
Main Authors: Zhang, Lixin, Sullivan, Peggy S., Goodman, Jerry C., Gunaratne, Preethi H., Marchetti, Dario
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078691/
https://ncbi.nlm.nih.gov/pubmed/21266359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1910
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