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Detection of ubiquitinated huntingtin species in intracellular aggregates
Protein conformation diseases, including polyglutamine (polyQ) diseases, result from the accumulation and aggregation of misfolded proteins. Huntington’s disease (HD) is one of nine diseases caused by an expanded polyQ repeat within the affected protein and is hallmarked by intracellular inclusion b...
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| Udgivet i: | Front Mol Neurosci |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4309157/ https://ncbi.nlm.nih.gov/pubmed/25674046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2015.00001 |
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