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Inhibition of matrix metalloproteinase-9 with low-dose doxycycline reduces acute lung injury induced by cardiopulmonary bypass

Objective: This study aims to demonstrate the protective effect of doxycycline, an exogenous inhibitor of matrix metalloproteinases-9 (MMP-9), in the acute lung injury induced by cardiopulmonary bypass (CPB). Methods: A total of 30 healthy mongrel dogs were randomly divided into three groups: Group...

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Détails bibliographiques
Publié dans:Int J Clin Exp Med
Auteurs principaux: Zhang, Chengxin, Gong, Wenhui, Liu, Haiyuan, Guo, Zhixiang, Ge, Shenglin
Format: Artigo
Langue:Inglês
Publié: e-Century Publishing Corporation 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307442/
https://ncbi.nlm.nih.gov/pubmed/25663995
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