Activities of cardiac tissue matrix metalloproteinases 2 and 9 are reduced by remote ischemic preconditioning in cardiosurgical patients with cardiopulmonary bypass

BACKGROUND: Transient episodes of ischemia in a remote organ or tissue (remote ischemic preconditioning, RIPC) can attenuate myocardial injury. Myocardial damage is associated with tissue remodeling and the matrix metalloproteinases 2 and 9 (MMP-2/9) are crucially involved in these events. Here we i...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Zitta, Karina, Meybohm, Patrick, Bein, Berthold, Gruenewald, Matthias, Lauer, Fabian, Steinfath, Markus, Cremer, Jochen, Zacharowski, Kai, Albrecht, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234318/
https://ncbi.nlm.nih.gov/pubmed/24712447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-94
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