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Doxycycline attenuates acute lung injury following cardiopulmonary bypass: involvement of matrix metalloproteinases

Acute lung injury (ALI) was one of the major complications after cardiopulmonary bypass (CPB). Matrix metalloproteinases (MMPs) play an important role in ALI following CPB. In this study, we investigated the effects of doxycycline (DOX), a potent MMP inhibitor, on MMP-9 and ALI in the rat model of C...

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Bibliografiska uppgifter
I publikationen:Int J Clin Exp Pathol
Huvudupphovsmän: Wang, Chang-Tian, Zhang, Lei, Wu, Hai-Wei, Wei, Lei, Xu, Biao, Li, De-Min
Materialtyp: Artigo
Språk:Inglês
Publicerad: e-Century Publishing Corporation 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270626/
https://ncbi.nlm.nih.gov/pubmed/25550781
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