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Inhibition of matrix metalloproteinase-9 with low-dose doxycycline reduces acute lung injury induced by cardiopulmonary bypass

Objective: This study aims to demonstrate the protective effect of doxycycline, an exogenous inhibitor of matrix metalloproteinases-9 (MMP-9), in the acute lung injury induced by cardiopulmonary bypass (CPB). Methods: A total of 30 healthy mongrel dogs were randomly divided into three groups: Group...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Zhang, Chengxin, Gong, Wenhui, Liu, Haiyuan, Guo, Zhixiang, Ge, Shenglin
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307442/
https://ncbi.nlm.nih.gov/pubmed/25663995
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