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Epigenetic Modification of Histone 3 Lysine 27: MEDIATOR SUBUNIT MED25 IS REQUIRED FOR THE DISSOCIATION OF POLYCOMB REPRESSIVE COMPLEX 2 FROM THE PROMOTER OF CYTOCHROME P450 2C9
The Mediator complex is vital for the transcriptional regulation of eukaryotic genes. Mediator binds to nuclear receptors at target response elements and recruits chromatin-modifying enzymes and RNA polymerase II. Here, we examine the involvement of Mediator subunit MED25 in the epigenetic regulatio...
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| Publicado en: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303677/ https://ncbi.nlm.nih.gov/pubmed/25391650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.579474 |
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