CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing

Trimethylation of histone H3 lysine 27 (H3K27me3) by Polycomb repressive complex 2 (PRC2) is essential for transcriptional silencing of Polycomb target genes, whereas acetylation of H3K27 (H3K27ac) has recently been shown to be associated with many active mammalian genes. The Trithorax protein (TRX)...

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Detalhes bibliográficos
Main Authors: Tie, Feng, Banerjee, Rakhee, Stratton, Carl A., Prasad-Sinha, Jayashree, Stepanik, Vincent, Zlobin, Andrei, Diaz, Manuel O., Scacheri, Peter C., Harte, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730368/
https://ncbi.nlm.nih.gov/pubmed/19700617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.037127
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