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Polycomb inhibits histone acetylation by CBP by binding directly to its catalytic domain

Drosophila Polycomb (PC), a subunit of Polycomb repressive complex 1 (PRC1), is well known for its role in maintaining repression of the homeotic genes and many others and for its binding to trimethylated histone H3 on Lys 27 (H3K27me3) via its chromodomain. Here, we identify a novel activity of PC:...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Tie, Feng, Banerjee, Rakhee, Fu, Chen, Stratton, Carl A., Fang, Ming, Harte, Peter J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760827/
https://ncbi.nlm.nih.gov/pubmed/26802126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515465113
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