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Polycomb inhibits histone acetylation by CBP by binding directly to its catalytic domain

Drosophila Polycomb (PC), a subunit of Polycomb repressive complex 1 (PRC1), is well known for its role in maintaining repression of the homeotic genes and many others and for its binding to trimethylated histone H3 on Lys 27 (H3K27me3) via its chromodomain. Here, we identify a novel activity of PC:...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Tie, Feng, Banerjee, Rakhee, Fu, Chen, Stratton, Carl A., Fang, Ming, Harte, Peter J.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760827/
https://ncbi.nlm.nih.gov/pubmed/26802126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515465113
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