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Polycomb inhibits histone acetylation by CBP by binding directly to its catalytic domain

Drosophila Polycomb (PC), a subunit of Polycomb repressive complex 1 (PRC1), is well known for its role in maintaining repression of the homeotic genes and many others and for its binding to trimethylated histone H3 on Lys 27 (H3K27me3) via its chromodomain. Here, we identify a novel activity of PC:...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Tie, Feng, Banerjee, Rakhee, Fu, Chen, Stratton, Carl A., Fang, Ming, Harte, Peter J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760827/
https://ncbi.nlm.nih.gov/pubmed/26802126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515465113
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