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Drosophila ESC-Like can substitute for ESC and becomes required for Polycomb silencing if ESC is absent

The Drosophila esc-like gene (escl) encodes a protein very similar to ESC. Like ESC, ESCL binds directly to the E(Z) histone methyltransferase via its WD region. In contrast to ESC, which is present at highest levels during embryogenesis and low levels thereafter, ESCL is continuously present throug...

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Detalhes bibliográficos
Main Authors: Kurzhals, Rebeccah L., Tie, Feng, Stratton, Carl A., Harte, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266587/
https://ncbi.nlm.nih.gov/pubmed/18048023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.10.025
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